Hyperthermic IntraPeritoneal Chemotherapy (HIPEC) is an innovative method of treating cancers originating in or spreading to the abdomen. Examples include colorectal cancer, appendiceal cancer, peritoneal mesothelioma, and pediatric malignancies. Typically,
cancers in the abdominal cavity are difficult to treat.
HIPEC is performed after a tumor is removed in surgery. The abdominal cavity is then bathed in heated chemotherapy effectively killing remaining cancer cells.
What happens during HIPEC?
First, visible tumors are surgically removed. This could leave microscopic cancer cells behind that may not be visible. A heated chemotherapy solution is used to target the left-behind cancer cells. HIPEC is directly administered into the abdominal cavity
through catheters. The goal of the chemotherapy is to eliminate cancer cells while preserving healthy cells. HIPEC is administered at a specific temperature range because cancer cells are killed at about 104°F while normal cells die at approximately
What to Expect Afterwards
Following cytoreductive surgery with HIPEC, average hospital stay is about 10 -12 days. Following discharge, our team will work to ensure the patient’s home care needs are met. While fatigue is common, it is imperative to remain active to prevent complications such as the formation of blood clots.
Side effects vary from individual to individual. These may include:
- nausea and vomiting
- formation of blood clots
- anastomotic leak
- increased likelihood of infection
- inability to consume enough calories following surgery