Diagnostic Procedures For Breast Cancer

The news of an abnormal mammogram or breast cancer diagnosis is both stressful and challenging. At Beaumont, an expedited diagnosis program quickly provides answers and coordinates care for benign and malignant breast diseases.

One call sets coordinated care in motion, from evaluation, diagnosis and treatment to follow-up. Comprehensive breast care components, which may require three or more appointments elsewhere, are usually accomplished in one visit to Beaumont, typically within days of the initial call.

Beaumont's facilities feature the most advanced diagnostic imaging (mammography) techniques and radiology procedures. Coordinating with the Multidisciplinary Breast Oncology Clinics, breast radiologists quickly diagnose patients using digital mammography, CT, MRI and PET scan imaging. A study of 840 patients at Beaumont proved that digital mammography provided better sensitivity and diagnosis for pre- or perimenopausal women younger than age 50. Such groundbreaking work explains why Beaumont is one of the busiest hospitals in Michigan for diagnostic radiology.

Beaumont 1st in SE Michigan to Offer Molecular Imaging to Detect Breast Cancer

Beaumont Hospital, Troy is the first hospital in Southeast Michigan to use a new breast cancer imaging tool to help physicians diagnose early-stage breast cancer. The new technology, called Breast-Specific Gamma Imaging, also known as Molecular Breast Imaging, or BSGI/MBI, may be used with selected patients as a secondary procedure to mammography, ultrasound and MRI.

How is breast cancer diagnosed?

It is important to remember that a lump or other changes in the breast, or an abnormal area on a mammogram, may be caused by cancer or by other, less serious problems.

Physical exam

To determine the cause of any signs or symptoms, your physician will perform a careful physical exam that includes a personal and family medical history as well as determining current overall health status. In addition, an examination may include the following:

  • palpation - carefully feeling the lump and the tissue around it - its size, its texture, and whether it moves easily. Benign lumps often feel different from cancerous ones.
  • nipple discharge examination - fluid may be collected from spontaneous nipple discharge and then sent to the lab to look for cancer cells. Most nipple secretions are not cancer, as an injury, infection, or benign tumor may cause discharge.
  • For women who are at high risk for breast cancer, a procedure called ductal lavage may be used. Ductal lavage is a procedure that collects cells from inside the milk ductal system - the location where most breast cancers begin.

Imaging test

In addition to a physical examination by your physician, an imaging test will be performed. Imaging tests may include one or more of the following:

  • diagnostic mammography - a diagnostic mammogram is an x-ray of the breast used to diagnose unusual breast changes, such as a lump, pain, nipple thickening or discharge, or a change in breast size or shape.
  • A diagnostic mammogram is also used to evaluate abnormalities detected on a screening mammogram. It is a basic medical tool and is appropriate in the workup of breast changes, regardless of a woman's age.
  • digital mammography (Also called full-field digital mammography, or FFDM)  - a type of mammography in which the images are electronically captured and stored on a computer, rather than x-ray film. The images are viewed on a computer screen.
  • Images can be changed, such as the degree of magnification, brightness or contrast, to help visualization. They can also be transmitted electronically. While this procedure currently costs more than standard mammography, studies are being done to see which type of mammography will be of more benefit to women for the long term. Some studies have found FFDM to be more accurate in finding cancers in women younger than 50.  Also, it has been found that women undergoing digital mammography do not have to return for additional studies as often as with standard mammography because the digital images have fewer questionable spots needing more investigation. However, not all hospitals and mammography facilities have digital equipment available.
  • ultrasonography - uses high-frequency sound waves, not heard by humans. The sound waves enter the breast and bounce back. The pattern of their echoes produces a picture called a sonogram, which is displayed on a screen. This exam is often used along with mammography.
  • scintimammography -  a specialized radiology procedure used to assess the breasts when other examinations have been inconclusive. Scintimammography, or breast scan, is a type of nuclear radiology procedure. This means that a tiny amount of a radioactive substance is used during the procedure to assist in the examination of the breasts. The radioactive substance, called a radionuclide (radiopharmaceutical or radioactive tracer), is absorbed by certain types of body tissues.
  • magnetic resonance imaging (MRI) - a diagnostic procedure that uses a combination of large magnets, radiofrequencies, and a computer to produce detailed images of organs and structures within the body.
  • In early 2007, the American Cancer Society (ACS) recommended new guidelines which include screening MRI with mammography for certain high-risk women. According to the ACS, contrast-enhanced MRI of the breasts has been shown to have a high sensitivity for detecting breast cancer in women both with or without symptoms.
  • MRI scans along with annual mammography should be considered for the following:
  • It is recommended that high-risk women begin screening mammography and screening MRI at the age of 30, unless they and their physicians agree that a different age is more appropriate.

Based on these exams, your physician may decide that no further tests are needed and no treatment is necessary. In such cases, your physician may want to check you regularly to watch for any changes.


Often, however, the physician must remove fluid or tissue from the breast to be sent to the lab to look for cancer cells. The procedure, called biopsy, may be performed using a needle to acquire a tissue sample or a surgical method.

A biopsy is a procedure performed to remove tissue or cells from the body for examination under a microscope. A breast biopsy is a procedure in which samples of breast tissue are removed with a special biopsy needle or during surgery to determine if cancer or other abnormal cells are present.

Biopsies may be performed under local or general anesthesia. There are several types of breast biopsy procedures. The type of biopsy performed will depend upon the location and size of the breast lump or abnormality.

Types of biopsy procedures

Types of breast biopsy procedures include, but are not limited to, the following:

  • fine needle aspiration biopsy - a very thin needle is placed into the lump or suspicious area to remove a small sample of fluid and/or tissue. No incision is necessary. A fine needle aspiration biopsy may be performed to help to differentiate a cyst from a lump.
  • core needle biopsy - a large needle is guided into a lump or suspicious area to remove a small cylinder of tissue (also called a core). No incision is necessary.
  • surgical biopsy (also called an open biopsy) - a surgeon removes part or all of a lump or suspicious area through an incision into the breast. There are two types of surgical biopsies. During an incisional biopsy, a small part of the lump is removed; whereas during an excisional biopsy, the entire lump is removed.
  • In some cases, if the breast lump is very small and deep and is difficult to locate, the wire localization technique may be used during surgery. With this technique, a special wire is placed into the lump under x-ray guidance. The surgeon follows this wire to help locate the breast lump.

Biopsy tools and techniques

There are special instruments and techniques that may be used to guide the needles and to assist with biopsy procedures. These include, but are not limited to, the following:

  • stereotactic biopsy - Stereotactic means "image guided" and, true to its name, stereotactic breast biopsy  finds the exact location of a breast lump or suspicious area by using a computer and mammogram results to create a three-dimensional (3D) picture of the breast. A sample of tissue is removed with a needle.
  • Mammotome® breast biopsy system (also called vacuum-assisted biopsy) - a type of tube is inserted into the breast lump or mass. The breast tissue is gently suctioned into the tube, and a rotating knife removes the tissue. In 1999, the US Food and Drug Administration (FDA) approved the use of the hand-held Mammotome device.
  • ultrasound-guided biopsy - a technique that uses a computer and a transducer that sends out ultrasonic sounds waves to create images of the breast lump or mass. This technique helps to guide the needle biopsy.
  • advanced breast biopsy instrumentation (ABBI)  - uses a rotating knife and cylinder to remove a large sample of tissue. Although this type of procedure has not received widespread acceptance, it is often possible to remove the entire breast lesion with this method.
  • Sentinel node biopsy- used to determine if cancer cells have spread to the lymph nodes. This surgical procedure may be performed during the initial diagnostic period to aid in staging of the breast cancer. This procedure involves injecting a dye and/or radioactive substance near the tumor. This injection helps to locate the lymph node closest to the tumor (sentinel node) - the one that is most likely to have cancer cells present if the cancer has spread. The surgeon removes the lymph node that absorbs the dye and radioactive substance and sends it to the pathologist to examine it closely for the presence of cancer cells.

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